In this work, monoethanolamine (MEA), an organosolv material, was used as an environmentally friendly process for kenaf whole-stem pulping. The pulping trials were carried out using MEA and MEA-anthraquinone (MEA-AQ) methods and the soda-AQ process as reference. The operating conditions such as the composition of the cooking liquor, the maximum cooking temperature and the cooking time, and a solid/liquor ratio during the pulping process were investigated systematically to establish optimal pulping conditions. The optimum cooking conditions for MEA pulping were 75% MEA concentration, 90-min cooking time, 160°C cooking temperature, 0.1% AQ, and liquor/kenaf ratio of 4/1. The laboratory-scale experimental results indicated that this pulping process is particularly well suited for the pulping of kenaf, where the whole stem was delignified to a low kappa number value of 19.8 and the pulp yield of 55.1%. This newly developed pulping process provided a high tensile, tear, and burst indices of 19.8 N·m/g, 5.9 mN·m2/g, and 1.43 kPa·m2/g, respectively. In addition, MEA-AQ kenaf whole-stem pulp showed superior mechanical properties in comparison with MEA and soda-AQ pulp. MEA-AQ pulping is a good alternative to soda-AQ pulping to produce high yield pulp with high strength from kenaf whole stem.